MTAP Antikörper (AA 97-196)

Produktnummer ABIN6654904

Der Kaninchen Monoklonal Anti-MTAP-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, MTAP in Proben von Human zu detektieren.

Kurzübersicht für MTAP Antikörper (AA 97-196) (ABIN6654904)

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MTAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: SMTP-1R

Produktdetails anti-MTAP Antikörper

Bindungsspezifität: AA 97-196

Aufreinigung: Purified

Reinheit: Protein A affinity chromatography

Immunogen: A portion of amino acids 97-196 from the human protein was used as the immunogen for the recombinant MTAP antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the recombinant MTAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Western blot: 1-2 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant MTAP antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu MTAP

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Andere Bezeichnung: MTAP

Hintergrund: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. [UniProt]

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process