Rekombinanter GP2 Antikörper (AA 35-179)

Produktnummer ABIN6654852

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch GP2 in WB, ELISA und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter GP2 Antikörper (AA 35-179) (ABIN6654852)

Target: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser GP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: GP2-2569R

Produktdetails anti-GP2 Antikörper

Bindungsspezifität: AA 35-179

Verwendungszweck: Recombinant Glycoprotein 2 Antibody / GP2 / ZAP75

Aufreinigung: Protein A affinity chromatography

Immunogen: A partial human recombinant protein corresponding to amino acids 35-179 was used as the immunogen for the recombinant Glycoprotein 2 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Glycoprotein 2 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant Glycoprotein 2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu GP2

Target: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Andere Bezeichnung: Glycoprotein 2

Hintergrund: GP2 (Glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.

UniProt: P55259