MUC2 Antikörper

Produktnummer ABIN6654848

Dieses Anti-MUC2-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von MUC2 in IHC (p). Geeignet für Human.

Kurzübersicht für MUC2 Antikörper (ABIN6654848)

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MUC2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: MLP-2970R

Produktdetails anti-MUC2 Antikörper

Aufreinigung: Purified

Reinheit: Protein A affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for the recombinant MUC2 antibody. Its epitope has been defined as GTQTP.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Titering of the recombinant MUC2 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant MUC2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu MUC2

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Andere Bezeichnung: MUC2 / Mucin 2

Hintergrund: Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon, in about 65 % of colonic carcinomas and about 40 % of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.