LGALS1/Galectin 1 Antikörper (AA 12-108)

Produktnummer ABIN6654651

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch LGALS1/Galectin 1 in IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LGALS1/Galectin 1 Antikörper (AA 12-108) (ABIN6654651)

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser LGALS1/Galectin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: GAL1-2499R

Produktdetails anti-LGALS1/Galectin 1 Antikörper

Bindungsspezifität: AA 12-108

Aufreinigung: Purified

Reinheit: Protein G affinity chromatography

Immunogen: A human recombinant partial protein corresponding to amino acids 12-108 was used as the immunogen for the recombinant Galectin 1 antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Titering of the recombinant Galectin 1 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant Galectin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Andere Bezeichnung: Galectin 1

Hintergrund: Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

Pathways: Carbohydrate Homeostasis