Rekombinanter LGALS1/Galectin 1 Antikörper (AA 12-108)

Produktnummer ABIN6654649

Der Kaninchen Monoklonal anti-LGALS1/Galectin 1 Antikörper wird verwendet zum Nachweis von LGALS1/Galectin 1 in Proben von Human. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für Rekombinanter LGALS1/Galectin 1 Antikörper (AA 12-108) (ABIN6654649)

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser LGALS1/Galectin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: GAL1-2499R

Produktdetails anti-LGALS1/Galectin 1 Antikörper

Bindungsspezifität: AA 12-108

Verwendungszweck: Recombinant Galectin 1 Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: A human recombinant partial protein corresponding to amino acids 12-108 was used as the immunogen for the recombinant Galectin 1 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Titering of the recombinant Galectin 1 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant Galectin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Andere Bezeichnung: Galectin 1

Hintergrund: Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

UniProt: P09382

Pathways: Carbohydrate Homeostasis