Rekombinanter DC-SIGN/CD209 Antikörper

Produktnummer ABIN6654643

Der Kaninchen Monoklonal anti-DC-SIGN/CD209 Antikörper wird verwendet zum Nachweis von DC-SIGN/CD209 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter DC-SIGN/CD209 Antikörper (ABIN6654643)

Target: DC-SIGN/CD209 (CD209) (CD209)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: C209-2749R

Produktdetails anti-DC-SIGN/CD209 Antikörper

Verwendungszweck: DC-SIGN Antibody / CD209 (azide and preservative free)

Aufreinigung: Protein A affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for the DC-SIGN antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the DC-SIGN antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the DC-SIGN antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: DC-SIGN

Hintergrund: DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

UniProt: Q9NNX6