Elastin Antikörper

Produktnummer ABIN6654574

Der Kaninchen Monoklonal Anti-Elastin-Antikörper wurde für IHC (p) validiert. Er ist geeignet, Elastin in Proben von Human zu detektieren.

Kurzübersicht für Elastin Antikörper (ABIN6654574)

Target: Elastin (ELN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Elastin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: ELN-3131R

Produktdetails anti-Elastin Antikörper

Aufreinigung: Purified

Reinheit: Protein A affinity chromatography

Immunogen: Recombinant full length human protein was used as the immunogen for the recombinant Elastin antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Titering of the recombinant Elastin antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant Elastin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu Elastin

Target: Elastin (ELN)

Andere Bezeichnung: Elastin

Hintergrund: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Pathways: Regulation of Actin Filament Polymerization