Rekombinanter Pituitary Growth Hormone 20kDa (AA 58-187) Antikörper

Produktnummer ABIN6654365

Der Maus Monoklonal anti-Pituitary Growth Hormone 20kDa Antikörper (Klon rGH-1450) (ABIN6654365) detektiert spezifisch Pituitary Growth Hormone 20kDa in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Pituitary Growth Hormone 20kDa (AA 58-187) Antikörper (ABIN6654365)

Target: Pituitary Growth Hormone 20kDa

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RGH-1450

Produktdetails

Bindungsspezifität: AA 58-187

Verwendungszweck: Recombinant GH Antibody (pituitary) / Growth Hormone

Aufreinigung: Protein G affinity chromatography

Immunogen: A human partial recombinant protein corresponding to amino acids 58-187 was used as the immunogen for this recombinant GH antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the recombinant GH antibody to be titered up or down for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant GH antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Antigendetails

Target: Pituitary Growth Hormone 20kDa

Andere Bezeichnung: Growth Hormone (pituitary)

Hintergrund: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

UniProt: P01241