CD44v3 Antikörper

Produktnummer ABIN6654324

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD44v3 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD44v3 Antikörper (ABIN6654324)

Target: CD44v3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 3G5

Produktdetails

Verwendungszweck: CD44v3 Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: An amino acid sequence from the variant 3 domain of CD44 was used as the immunogen for the CD44v3 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Titering of the CD44v3 antibody may be required for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CD44v3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Antigendetails

Target: CD44v3

Hintergrund: This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 Molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. It is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.

UniProt: P16070