PDCD10 Antikörper (AA 1-212)

Produktnummer ABIN6654194

Produktdetails anti-PDCD10 Antikörper

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Bindungsspezifität: AA 1-212

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDCD10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: Human PDCD10 recombinant protein (amino acids M1-A212) was used as the immunogen for the PDCD10 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PDCD10 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the PDCD10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PDCD10

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Andere Bezeichnung: PDCD10 (PDCD10 Produkte)

Hintergrund: Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene. This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

UniProt: Q9BUL8