CCL8 Antikörper (AA 24-97)

Produktnummer ABIN6654185

Dieses Anti-CCL8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCL8 in IHC (p) und ELISA (Capture). Geeignet für Maus und Ratte.

Kurzübersicht für CCL8 Antikörper (AA 24-97) (ABIN6654185)

Target: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL8 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)

Produktdetails anti-CCL8 Antikörper

Bindungsspezifität: AA 24-97

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids G24-P97 from the mouse protein were used as the immunogen for the Mcp2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Mcp2 antibody should be determined by the researcher.\. IHC (FFPE): 1-2 μg/mL,ELISA (Capture): 1-5 μg/mL (recombinant mouse protein)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Mcp2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CCL8

Target: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Andere Bezeichnung: Mcp2 / Ccl8

Hintergrund: CCL8, also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene. It is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B, CCR3 and CCR5.

UniProt: Q9Z121