Arylsulfatase A Antikörper

Produktnummer ABIN6654013

Produktdetails anti-Arylsulfatase A Antikörper

Target: Arylsulfatase A (ARSA)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Arylsulfatase A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: Protein G affinity

Immunogen: Amino acids QALKQLQLLKAQLDAAVTFGPSQVARGED were used as the immunogen for the ARSA antibody.

Klon: 4C10

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ARSA antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Flow Cytometry: 1-3 μg/10^6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the ARSA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Arylsulfatase A

Target: Arylsulfatase A (ARSA)

Andere Bezeichnung: ARSA (ARSA Produkte)

Hintergrund: Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

UniProt: P15289