Der Maus Monoklonal Anti-Thrombomodulin-Antikörper wurde für FACS, IHC (p) und IHC (fro) validiert. Er ist geeignet, Thrombomodulin in Proben von Human und Kaninchen zu detektieren.
Produktnummer ABIN6653774
Kurzübersicht für Thrombomodulin Antikörper (ABIN6653774)
THBD
Reaktivität: Human
WB, FACS, IF
Wirt: Kaninchen
Polyclonal
RB56919
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody undiluted at -20 °C.
Target
Thrombomodulin (THBD)
Andere Bezeichnung
CD141 / THBD
Hintergrund
CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII, thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.Synonyms: Fetomodulin, THRM, Thrombomodulin