TGFB2 Antikörper

Produktnummer ABIN2838086

Dieses Anti-TGFB2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TGFB2 in WB, IHC (p) und IF. Geeignet für Human.

Kurzübersicht für TGFB2 Antikörper (ABIN2838086)

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TGFB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Klon: 220ct16-4-3-1

Produktdetails anti-TGFB2 Antikörper

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This TGFB2 monoclonal antibody is generated from mouse immunized with TGFB2 recombinant protein.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:100~1000. WB: 1:500-1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50. IHC: 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu TGFB2

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Andere Bezeichnung: TGFB2

Hintergrund: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molekulargewicht: 47748

Gen-ID: 7042

NCBI Accession: NP_001129071, NP_003229

UniProt: P61812

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus