EZH2 Antikörper

Produktnummer ABIN659002

Dieses Maus Monoklonal-Antikörper erkennt spezifisch EZH2 in WB, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für EZH2 Antikörper (ABIN659002)

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EZH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 144CT2-1-1-5

Produktdetails anti-EZH2 Antikörper

Homologie: Pr

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This EZH2 antibody is generated from mouse immunized with EZH2 recombinant protein.

Isotyp: IgG1, Ig kappa

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. IF: 1:25. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. IHC-P: 1:25. IHC: 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-EZH2 Antikörper (ABIN659002)

Zhang, Ji, Liu, Lei, Li, Ji, Yuan, Jiao: "Ezh2 regulates adult hippocampal neurogenesis and memory." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 15, pp. 5184-99, (2014) (PubMed).

Details zu EZH2

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Andere Bezeichnung: EZH2

Hintergrund: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Two transcript variants encoding distinct isoforms have been identified for this gene.

Molekulargewicht: 85363

Gen-ID: 2146

NCBI Accession: NP_001190176, NP_001190177, NP_001190178, NP_004447, NP_694543

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation