Kurzübersicht für TNINI3 (AA 52-79) Antikörper (ABIN658916)
Target
TNINI3
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Applikation
Western Blotting (WB)
Klon
358CT10-3-6
Bindungsspezifität
AA 52-79
Homologie
B, Hs, Rb
Aufreinigung
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Immunogen
This TNINI3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 52-79 amino acids from human TNINI3.
Isotyp
IgM
Applikationshinweise
WB: 1:500~8000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
TNINI3
Hintergrund
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).