BAG2 Antikörper (C-Term)

Produktnummer ABIN657974

Der Kaninchen Polyklonal Anti-BAG2-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, BAG2 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für BAG2 Antikörper (C-Term) (ABIN657974)

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB34133

Produktdetails anti-BAG2 Antikörper

Bindungsspezifität: AA 148-176, C-Term

Homologie: B, M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human BAG2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: BAG2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-BAG2 Antikörper (ABIN657974)

He, Wu, Su, Zhang, Pan, Wei, Fang, Li, Wang, Sun: "JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis." in: The Journal of biological chemistry, Vol. 291, Issue 9, pp. 4684-97, (2016) (PubMed).

Details zu BAG2

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Andere Bezeichnung: BAG2

Hintergrund: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq].

Molekulargewicht: 23772

Gen-ID: 9532

NCBI Accession: NP_004273

UniProt: O95816