PLGRKT Antikörper (AA 1-50)
Kurzübersicht für PLGRKT Antikörper (AA 1-50) (ABIN6579700)
Target
Alle PLGRKT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Plasminogen receptor Antibody
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Spezifität
- Plasminogen receptor Polyclonal Antibody detects endogenous levels of Plasminogen receptor
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized peptide derived from the Internal region of human PLGRKT. AA range:1-50
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000,IHC 1:50-300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- PLGRKT (Plasminogen Receptor, C-Terminal Lysine Transmembrane Protein (PLGRKT))
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Andere Bezeichnung
- PLGRKT
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Hintergrund
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Synonyms: Plasminogen receptor (KT) (Plg-R(KT))
Background: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
Gene Name: PLGRKT
Protein Name: Plasminogen receptor
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Molekulargewicht
- 17 kDa
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Gen-ID
- 55848
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UniProt
- Q9HBL7
Target
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