ZNF384 Antikörper (AA 1-50)

Produktnummer ABIN6579679

Der Kaninchen Polyklonal anti-ZNF384 Antikörper wird verwendet zum Nachweis von ZNF384 in Proben von Human und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für ZNF384 Antikörper (AA 1-50) (ABIN6579679)

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF384 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ZNF384 Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: ZNF384 Antibody

Spezifität: ZNF384 Polyclonal Antibody detects endogenous levels of ZNF384 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human ZNF384. AA range:1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ZNF384

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Andere Bezeichnung: ZNF384

Hintergrund:

Synonyms: ZNF384; CAGH1; CIZ; NMP4; TNRC1; Zinc finger protein 384; CAG repeat protein 1; CAS-interacting zinc finger protein; Nuclear matrix transcription factor 4; Nuclear matrix protein 4; Trinucleotide repeat-containing gene 1 protein

Background: zinc finger protein 384(ZNF384) Homo sapiens This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011],

Gene Name: ZNF384

Protein Name: Zinc finger protein 384

Molekulargewicht: 63 kDa

Gen-ID: 171017

OMIM: 609951

UniProt: Q8TF68