GDF7 Antikörper (AA 321-370)

Produktnummer ABIN6579637

Der Kaninchen Polyklonal anti-GDF7 Antikörper (ABIN6579637) detektiert spezifisch GDF7 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GDF7 Antikörper (AA 321-370) (ABIN6579637)

Target: GDF7 (Growth Differentiation Factor 7 (GDF7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GDF7 Antikörper

Bindungsspezifität: AA 321-370

Verwendungszweck: GDF-7 Antibody

Spezifität: GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF7. AA range:321-370

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GDF7

Target: GDF7 (Growth Differentiation Factor 7 (GDF7))

Andere Bezeichnung: GDF7

Hintergrund:

Synonyms: GDF7; Growth/differentiation factor 7; GDF-7

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016],

Gene Name: GDF7

Protein Name: Growth/differentiation factor 7

Molekulargewicht: 46 kDa

Gen-ID: 151449

OMIM: 604651

UniProt: Q7Z4P5

Pathways: Tube Formation