GDF6 Antikörper (AA 311-360)

Produktnummer ABIN6579634

Der Kaninchen Polyklonal anti-GDF6 Antikörper wird verwendet zum Nachweis von GDF6 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für GDF6 Antikörper (AA 311-360) (ABIN6579634)

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GDF6 Antikörper

Bindungsspezifität: AA 311-360

Verwendungszweck: GDF-6 Antibody

Spezifität: GDF-6 Polyclonal Antibody detects endogenous levels of GDF-6 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF6. AA range:311-360

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GDF6

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Andere Bezeichnung: GDF6

Hintergrund:

Synonyms: GDF6, GDF16, Growth/differentiation factor 6, GDF-6, Growth/differentiation factor 16

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],

Gene Name: GDF6

Protein Name: Growth/differentiation factor 6

Molekulargewicht: 50 kDa

Gen-ID: 392255

OMIM: 118100

UniProt: Q6KF10