Der Kaninchen Polyklonal Anti-USO1-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, USO1 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This USO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 932-960 amino acids from the C-terminal region of human USO1.
USO1
Reaktivität: Human, Maus
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000. IHC-P: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
USO1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Haltbarkeit
6 months
Sui, Li, Xing, Cao, Wang, Gong, Zhang: "Lentivirus-mediated silencing of USO1 inhibits cell proliferation and migration of human colon cancer cells." in: Medical oncology (Northwood, London, England), Vol. 32, Issue 8, pp. 658, (2015) (PubMed).
Target
USO1
(USO1 Homolog, Vesicle Docking Protein (USO1))
Andere Bezeichnung
USO1
Hintergrund
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.