CD207 Antikörper (AA 61-110)

Produktnummer ABIN6579543

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CD207 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CD207 Antikörper (AA 61-110) (ABIN6579543)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD207 Antikörper

Bindungsspezifität: AA 61-110

Verwendungszweck: CD207 Antibody

Spezifität: CD207 Polyclonal Antibody detects endogenous levels of CD207 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD207. AA range:61-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: CD207

Hintergrund:

Synonyms: CD207, CLEC4K, C-type lectin domain family 4 member K, Langerin, CD207

Background: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],

Gene Name: CD207

Protein Name: C-type lectin domain family 4 member K

Molekulargewicht: 36 kDa

Gen-ID: 50489

OMIM: 604862

UniProt: Q9UJ71