ITGA6 Antikörper (AA 901-950)
Kurzübersicht für ITGA6 Antikörper (AA 901-950) (ABIN6579458)
Target
Alle ITGA6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 901-950
-
Verwendungszweck
- Integrin α6 Antibody
-
Spezifität
- Integrin α6 Polyclonal Antibody detects endogenous levels of Integrin α6 protein.
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- The antiserum was produced against synthesized peptide derived from the Internal region of human ITGA6. AA range:901-950
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C/1 year
-
Haltbarkeit
- 12 months
-
-
- ITGA6 (Integrin, alpha 6 (ITGA6))
-
Andere Bezeichnung
- ITGA6
-
Hintergrund
-
Synonyms: ITGA6, Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD49f
Background: integrin subunit alpha 6(ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Gene Name: ITGA6
Protein Name: Integrin alpha-6
-
Molekulargewicht
- '125 kDa
-
Gen-ID
- 3655
-
OMIM
- 182120
-
UniProt
- P23229
-
Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
Target
-