ANGPTL4 Antikörper (AA 301-350)

Produktnummer ABIN6579282

Der Kaninchen Polyklonal anti-ANGPTL4 Antikörper (ABIN6579282) detektiert spezifisch ANGPTL4 in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für ANGPTL4 Antikörper (AA 301-350) (ABIN6579282)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-ANGPTL4 Antikörper

Bindungsspezifität: AA 301-350

Verwendungszweck: Angptl4 Antibody

Spezifität: Angptl4 Polyclonal Antibody detects endogenous levels of Angptl4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ANGPTL4. AA range:301-350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Andere Bezeichnung: ANGPTL4

Hintergrund:

Synonyms: ANGPTL4, ARP4, HFARP, PGAR, PP1158, PSEC0166, Angiopoietin-related protein 4, Angiopoietin-like protein 4, Hepatic fibrinogen/angiopoietin-related protein, HFARP

Background: This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013],

Gene Name: ANGPTL4

Protein Name: Angiopoietin-related protein 4

Molekulargewicht: 45 kDa

Gen-ID: 51129

OMIM: 605910

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha