PNPLA6 Antikörper (AA 1031-1080)

Produktnummer ABIN6579261

Der Kaninchen Polyklonal anti-PNPLA6 Antikörper wird verwendet zum Nachweis von PNPLA6 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für PNPLA6 Antikörper (AA 1031-1080) (ABIN6579261)

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNPLA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PNPLA6 Antikörper

Bindungsspezifität: AA 1031-1080

Verwendungszweck: NTE Antibody

Spezifität: NTE Polyclonal Antibody detects endogenous levels of NTE protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PNPLA6. AA range:1031-1080

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PNPLA6

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Andere Bezeichnung: PNPLA6

Hintergrund:

Synonyms: PNPLA6, NTE, Neuropathy target esterase, Patatin-like phospholipase domain-containing protein 6

Background: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

Gene Name: PNPLA6

Protein Name: Neuropathy target esterase

Molekulargewicht: 149 kDa

Gen-ID: 10908

OMIM: 603197

UniProt: Q8IY17

Pathways: Ribonucleoside Biosynthetic Process