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RFX5 Antikörper (AA 237-266)

This anti-RFX5 antibody (ABIN657925) is a Rabbit Polyclonal antibody detecting RFX5 in WB. Suitable for Human.
Produktnummer ABIN657925

Kurzübersicht für RFX5 Antikörper (AA 237-266) (ABIN657925)

Target

Alle RFX5 Antikörper anzeigen
RFX5 (Regulatory Factor X 5 (RFX5))

Reaktivität

  • 29
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
Human

Wirt

  • 26
  • 3
  • 1
Kaninchen

Klonalität

  • 28
  • 2
Polyklonal

Konjugat

  • 26
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RFX5 Antikörper ist unkonjugiert

Applikation

  • 28
  • 18
  • 6
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)

Klon

RB33870
  • Bindungsspezifität

    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 237-266

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This RFX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the Central region of human RFX5.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    RFX5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    Haltbarkeit

    6 months
  • Target

    RFX5 (Regulatory Factor X 5 (RFX5))

    Andere Bezeichnung

    RFX5

    Hintergrund

    A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq].

    Molekulargewicht

    65323

    Gen-ID

    5993

    NCBI Accession

    NP_000440, NP_001020774

    UniProt

    P48382
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