This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CBX8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 197-230 amino acids from the Central region of human CBX8.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
CBX8
(Chromobox Homolog 8 (CBX8))
Andere Bezeichnung
CBX8
Hintergrund
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.