Der Kaninchen-Polyklonal Anti-Topoisomerase I-Antikörper wurde für WB und IF validiert. Er ist geeignet zum Nachweis von Topoisomerase I in Proben aus Human.
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This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TOP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human TOP1.
TOP1
Reaktivität: Human
ELISA, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
IF: 1:10~50. WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
TOP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Haltbarkeit
6 months
Target
Topoisomerase I (TOP1)
(Topoisomerase (DNA) I (TOP1))
Andere Bezeichnung
TOP1
Hintergrund
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.