Der Kaninchen Polyklonal Anti-Retinoic Acid Receptor alpha-Antikörper wurde für WB, IF, FACS und IHC (p) validiert. Er ist geeignet, Retinoic Acid Receptor alpha in Proben von Human und Maus zu detektieren.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-349 amino acids from the C-terminal region of human RARA.
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.