MARCH11
(Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))
Reaktivität
Human
Wirt
Kaninchen
Klonalität
Polyklonal
Konjugat
Dieser MARCH11 Antikörper ist unkonjugiert
Applikation
Western Blotting (WB)
Klon
RB31539
Bindungsspezifität
AA 308-337, C-Term
Homologie
M, Rat
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MARCH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human MARCH11.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
MARCH11 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Haltbarkeit
6 months
Target
MARCH11
(Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))
Andere Bezeichnung
MARCH11
Hintergrund
MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).