PPP4C Antikörper (AA 160-189)
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- Target Alle PPP4C Antikörper anzeigen
- PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))
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Bindungsspezifität
- AA 160-189
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PPP4C Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Zf, B, M, Rb, Rat, X
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PPP4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-189 amino acids from the Central region of human PPP4C.
- Klon
- RB33771
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PPP4C Primärantikörper
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anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibody
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anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
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anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyPPP4C Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1E8 unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) antibodyPPP4C Reaktivität: Human, Maus, Ratte WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 218-307) antibodyPPP4C Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyPPP4C Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen, Zebrafisch (Danio rerio), Fledermaus, Hamster, Affe, Xenopus laevis, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- PPP4C Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))
- Andere Bezeichnung
- PPP4C (PPP4C Produkte)
- Hintergrund
- Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity).
- Molekulargewicht
- 35080
- Gen-ID
- 5531
- NCBI Accession
- NP_002711
- UniProt
- P60510
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