Selenoprotein K Antikörper (AA 32-61)

Produktnummer ABIN657518

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Selenoprotein K Antikörper wird verwendet zum Nachweis von Selenoprotein K in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für Selenoprotein K Antikörper (AA 32-61) (ABIN657518)

Target: Selenoprotein K (SELK)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Selenoprotein K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB32894

Produktdetails anti-Selenoprotein K Antikörper

Bindungsspezifität: AA 32-61

Homologie: Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the Central region of human SELK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: SELK Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-Selenoprotein K Antikörper (ABIN657518)

Fredericks, Hoffmann, Rose, Osterheld, Hess, Mercier, Hoffmann: "Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 46, pp. 16478-83, (2014) (PubMed).

Details zu Selenoprotein K

Target: Selenoprotein K (SELK)

Andere Bezeichnung: SELK

Hintergrund: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant.

Molekulargewicht: 10645

Gen-ID: 58515

NCBI Accession: NP_067060

UniProt: Q9Y6D0