Synonyms: GAA 5,GAA5,GABA(A) receptor subunit alpha-5,GABRA 5,Gabra5,Gamma aminobutyric acid GABA A receptor alpha 5,Gamma aminobutyric acid GABA A receptor alpha 5 precursor,Gamma aminobutyric acid receptor alpha 5 subunit precursor GABA A receptor,Gamma-aminobutyric acid receptor subunit alpha-5,GBRA5,GC138184
Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.