Nodal Antikörper (Nodal Homolog (Mouse))

Details for Product anti-NODAL Antibody No. ABIN6572072
Antigen
  • NODAL
  • Tg.413d
  • HTX5
  • nodal4
  • nodal4-A
  • nr4
  • xnr4
  • Xnr-1
  • nodal
  • nr1
  • nr1-A
  • nodal growth differentiation factor
  • nodal homolog (mouse)
  • nodal
  • nodal growth differentiation factor L homeolog
  • nodal homolog 1 L homeolog
  • Nodal
  • NODAL
  • nodal.L
  • nodal1.L
Reaktivität
Human, Ratte (Rattus)
66
38
38
4
4
4
3
3
1
1
1
Wirt
Kaninchen
49
12
8
1
Klonalität
Polyklonal
Konjugat
Dieser Nodal Antikörper ist unkonjugiert
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
44
32
13
11
9
3
2
2
2
2
1
1
Optionen
Immunogen Recombinant protein of human NODAL
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere Nodal products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung NODAL (NODAL Antibody Abstract)
Hintergrund

Synonyms: HTX5,MGC138230,Nodal,Nodal Growth Differentiation Factor,nodal homolog (mouse),Nodal homolog,Nodal,Mouse,Homolog,NODAL

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.

Molekulargewicht

Observed_MW: 44kDa

Calculated_MW: 39kDa

Gen-ID 4838
UniProt Q96S42
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of Endopeptidase Activity
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Nodal Homolog (Mouse) (NODAL) antibody (ABIN6572072) Western blot analysis of extracts of various cell lines, using NODAL antibody.
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