Nodal Antikörper

Produktnummer ABIN6572072

Produktdetails anti-Nodal Antikörper

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nodal Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human NODAL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Nodal

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Andere Bezeichnung: NODAL (NODAL Produkte)

Synonyme: NODAL antikoerper, Tg.413d antikoerper, HTX5 antikoerper, nodal4 antikoerper, nodal4-A antikoerper, nr4 antikoerper, xnr4 antikoerper, Xnr-1 antikoerper, nodal antikoerper, nr1 antikoerper, nr1-A antikoerper, nodal growth differentiation factor antikoerper, nodal homolog (mouse) antikoerper, nodal antikoerper, nodal growth differentiation factor L homeolog antikoerper, nodal homolog 1 L homeolog antikoerper, Nodal antikoerper, NODAL antikoerper, nodal.L antikoerper, nodal1.L antikoerper

Hintergrund:

Synonyms: HTX5,MGC138230,Nodal,Nodal Growth Differentiation Factor,nodal homolog (mouse),Nodal homolog,Nodal,Mouse,Homolog,NODAL

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.

Molekulargewicht:

Observed_MW: 44kDa

Calculated_MW: 39kDa

Gen-ID: 4838

UniProt: Q96S42

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of Endopeptidase Activity