CLEC7A Antikörper (C-Type Lectin Domain Family 7, Member A)

Details for Product anti-CLEC7A Antibody No. ABIN6572064
Antigen
  • CLEC7A
  • BGR
  • Clecsf12
  • beta-GR
  • CANDF4
  • CLECSF12
  • DECTIN1
  • Clec7b
  • RGD1565140
  • C-type lectin domain containing 7A
  • C-type lectin domain family 7, member a
  • CLEC7A
  • Clec7a
Reaktivität
Human, Maus, Ratte (Rattus)
106
87
13
2
Wirt
Kaninchen
72
46
38
Klonalität
Polyklonal
Konjugat
Dieser CLEC7A Antikörper ist unkonjugiert
25
14
12
6
5
4
4
2
2
2
2
2
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
79
47
35
32
18
15
13
13
8
4
2
2
Optionen
Immunogen A synthetic peptide of human CLEC7A
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere CLEC7A products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung CLEC7A (CLEC7A Antibody Abstract)
Hintergrund

Synonyms: Beta GR,Beta-glucan receptor,BGR,C type calcium dependent carbohydrate recognition domain lectin superfamily member 12,C type lectin domain family 7 member a,C-type lectin domain family 7 member A,C-type lectin superfamily member 12,CANDF4,CLC7A,CLEC7A,CLEC7A protein,Clecsf12,DC-associated C-type lectin 1,Dectin 1,DECTIN 1 receptor,Dectin-1,Dectin1,Dendritic cell associated C type lectin 1,Dendritic cell-associated C-type lectin 1,Lectin like receptor 1,Putative transmembrane protein dectin 1

Background: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Molekulargewicht

Observed_MW: 31kDa

Calculated_MW: 5kDa/8kDa/13-27kDa

Gen-ID 64581
UniProt Q9BXN2
Pathways Activation of Innate immune Response
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) antibody (ABIN6572064) Western blot analysis of extracts of various cell lines, using CLEC7A antibody.
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