CAPN10 Antikörper

Produktnummer ABIN6572052

Dieses Anti-CAPN10-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CAPN10 in WB. Geeignet für Human.

Kurzübersicht für CAPN10 Antikörper (ABIN6572052)

Target: CAPN10 (Calpain 10 (CAPN10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAPN10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CAPN10 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CAPN10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000 - 1:4000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CAPN10

Target: CAPN10 (Calpain 10 (CAPN10))

Andere Bezeichnung: CAPN10

Hintergrund:

Synonyms: Calcium activated neutral protease,Calcium activated neutral proteinase 10,Calcium-activated neutral proteinase 10,calpain like protease CAPN10,Calpain-10,Calpain10,CAN10,CANP 10,CANP10,CAPN 10,CAPN10,EC 3.4.22.,KIAA1845,NIDDM1

Background: Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.

Molekulargewicht:

Observed_MW: 75kDa

Calculated_MW: 15kDa/29kDa/49kDa/57kDa/60kDa/74kDa

Gen-ID: 11132

UniProt: Q9HC96

Pathways: Positive Regulation of Peptide Hormone Secretion