RPE65 Antikörper (Retinal Pigment Epithelium-Specific Protein 65kDa)

Details for Product anti-RPE65 Antibody No. ABIN6572041
Antigen
  • LCA2
  • RP20
  • mRPE65
  • rd12
  • sRPE65
  • 65kDa
  • A930029L06Rik
  • Mord1
  • DRPE65
  • RPE65
  • anon-WO0148162.1
  • anon-WO0148163.1
  • beta-diox
  • DmelCG9347
  • CG9347
  • MGC52887
  • MGC154296
  • MGC85437
  • rpe65
  • RPE56c
  • si:ch211-198n5.12
  • RPE56a
  • rpepa
  • zgc:73213
  • RPE65, retinoid isomerohydrolase
  • retinal pigment epithelium 65
  • neither inactivation nor afterpotential B
  • retinal pigment epithelium-specific protein 65kDa S homeolog
  • retinal pigment epithelium-specific protein 65kDa L homeolog
  • RPE65 homolog
  • retinal pigment epithelium-specific protein 65kDa
  • retinal pigment epithelium-specific protein 65c
  • retinal pigment epithelium-specific protein 65a
  • RPE65
  • Rpe65
  • ninaB
  • rpe65.S
  • rpe65.L
  • rpe65
  • rpe65c
  • rpe65a
Reaktivität
Human, Maus, Ratte (Rattus)
47
39
39
10
2
1
1
Wirt
Kaninchen
46
8
1
Klonalität
Polyklonal
Konjugat
Dieser RPE65 Antikörper ist unkonjugiert
6
4
3
2
2
2
2
2
2
1
1
1
1
1
Applikation
Western Blotting (WB)
35
16
13
10
5
3
3
3
3
3
2
1
Optionen
Immunogen Recombinant protein of human RPE65
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere RPE65 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung RPE65 (RPE65 Antibody Abstract)
Hintergrund

Synonyms: All-trans-retinyl-palmitate hydrolase,LCA 2,LCA2,Leber congenital amaurosis ,mRPE 65,mRPE65,p63,rd 12,rd12,Retinal pigment epithelium specific 61 kDa protein,Retinal pigment epithelium specific 65 kDa protein,Retinal pigment epithelium specific protein ,Retinal pigment epithelium specific protein 65  kDa,Retinal pigment epithelium-specific 65 kDa protein,Retinitis pigmentosa 20 ,Retinoid isomerohydrolase,Retinol isomerase,RP 20,RP20,RPE 65,RPE65,RPE65,sRPE 65,sRPE65

Background: This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa.

Molekulargewicht

Observed_MW: 61kDa

Calculated_MW: 60kDa

Gen-ID 6121
UniProt Q16518
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibody (ABIN6572041) Western blot analysis of extracts of various cell lines, using RPE65 antibody.
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