GIPR Antikörper (Gastric Inhibitory Polypeptide Receptor)

Details for Product anti-GIPR Antibody No. ABIN6572025
Antigen
  • GIPR
  • PGQTL2
  • GIP-R
  • Gm1081
  • Gm160
  • Gippr
  • RATGIPPR
  • gastric inhibitory polypeptide receptor
  • glucagon receptor
  • GIPR
  • LOC100303705
  • Gipr
Reaktivität
Human, Maus, Ratte (Rattus)
114
34
26
4
4
3
3
2
2
2
Wirt
Kaninchen
107
7
Klonalität
Polyklonal
Konjugat
Dieser GIPR Antikörper ist unkonjugiert
7
6
6
5
5
5
2
2
2
2
2
2
1
1
1
1
1
Applikation
Western Blotting (WB)
60
55
28
25
13
8
4
3
1
1
Optionen
Immunogen Recombinant protein of human GIPR
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere GIPR products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung GIPR (GIPR Antibody Abstract)
Hintergrund

Synonyms: Gastric inhibitory polypeptide receptor,GIP R,GIP-R,Gippr,Gipr,GIPR,Glucose dependent insulinotropic polypeptide receptor,Glucose-dependent insulinotropic polypeptide receptor,Gm1081,Gm160,INSULINOTROPIC POLYPEPTIDE RECEPTOR,GLUCOSE DEPENDENT,MGC126722,PGQTL2,RATGIPPR

Background: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

Molekulargewicht

Observed_MW: 53kDa

Calculated_MW: 48kDa/49kDa/53kDa

Gen-ID 2696
UniProt P48546
Pathways Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
Applikations-hinweise WB 1:200 - 1:500
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Gastric Inhibitory Polypeptide Receptor (GIPR) antibody (ABIN6572025) Western blot analysis of extracts of various cell lines, using GIPR antibody.
Haben Sie etwas anderes gesucht?