Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) (TIMM8A) Antikörper

Details zu Produkt Nr. ABIN6572020
Antigen
  • TIMM8A
  • ddp
  • tim8a
  • timm8a
  • DDP
  • DDP1
  • DFN1
  • MTS
  • TIM8
  • im:6896085
  • zgc:100916
  • Ddp1
  • Timm8a
  • DXHXS1274E
  • Fci-12
  • Tim8a
  • translocase of inner mitochondrial membrane 8 homolog A (yeast)
  • translocase of inner mitochondrial membrane 8A
  • translocase of inner mitochondrial membrane 8 homolog A1 (yeast)
  • translocase of inner mitochondrial membrane 8A1
  • TIMM8A
  • timm8a
  • Timm8a1
Reaktivität
Human, Maus
45
31
26
1
1
Wirt
Kaninchen
35
10
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
26
14
13
6
5
4
1
1
Optionen
Immunogen Recombinant protein of human TIMM8A
Isotyp IgG
Reinigung Affinity purification
Antigen
Andere Bezeichnung TIMM8A (TIMM8A Antibody Abstract)
Hintergrund

Synonyms: DDP 1,DDP,DDP1,Deafness dystonia protein 1,Deafness/dystonia peptide,DFN 1,DFN1,MGC12262,Mitochondrial import inner membrane translocase subunit Tim8 A,MTS,TIM 8A,TIM8,TIM8A,TIM8A,TIMM 8A,timm8a,Translocase of inner mitochondrial membrane 8 homolog A,X linked deafness dystonia protein,X-linked deafness dystonia protein

Background: This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht

Observed_MW: 11kDa

Calculated_MW: 10kDa

Gen-ID 1678
UniProt O60220
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) (TIMM8A) antibody (ABIN6572020) Western blot analysis of extracts of various cell lines, using TIMM8A antibody.
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