BCKDHA Antikörper

Produktnummer ABIN6572016

Der Kaninchen Polyklonal anti-BCKDHA Antikörper (ABIN6572016) detektiert spezifisch BCKDHA in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für BCKDHA Antikörper (ABIN6572016)

Target: BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCKDHA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BCKDHA Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human BCKDHA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BCKDHA

Target: BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))

Andere Bezeichnung: BCKDHA

Hintergrund:

Synonyms: Branched chain alpha keto acid dehydrogenase E1 component alpha polypeptide, FLJ45695, OVD1A,2 oxoisovalerate dehydrogenase (lipoamide),2 oxoisovalerate dehydrogenase subunit alpha, mitochondrial ,2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial,BCKDE1A,BCKDH E1 alpha,BCKDH E1-alpha,BCKDHA,Branched chain alpha keto acid dehydrogenase E1 component alpha chain,Branched chain keto acid dehydrogenase E1 alpha polypeptide,Branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease),Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain,MSU,MSUD1,ODBA

Background: The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 50kDa

Calculated_MW: 50kDa

Gen-ID: 593

UniProt: P12694