CSE1L Antikörper (CSE1 Chromosome Segregation 1-Like (Yeast))

Details for Product anti-CSE1L Antibody No. ABIN6571992
Antigen
  • BcDNA:LD14270
  • CAS
  • CG13281
  • Dcas
  • Dmel\\CG13281
  • cas
  • dcas
  • l(2)k03902
  • CSE1L
  • XPO2
  • Exportin-2
  • DKFZp459E1929
  • 2610100P18Rik
  • AA407533
  • Capts
  • Cas
  • Xpo2
  • xpo2
  • CSE1
  • CAS/CSE1 segregation protein
  • chromosome segregation 1 like
  • exportin-2
  • chromosome segregation 1-like (S. cerevisiae)
  • CSE1 chromosome segregation 1-like (yeast)
  • CSE1 chromosome segregation 1-like L homeolog
  • Cas
  • CSE1L
  • LOC100542094
  • cse1l
  • Cse1l
  • cse1l.L
Reaktivität
Human
74
23
15
9
7
6
5
4
3
3
2
1
1
1
Wirt
Kaninchen
45
29
1
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
74
37
37
24
23
22
7
4
3
3
2
2
1
1
1
Optionen
Immunogen A synthetic peptide of human CSE1L
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere CSE1L products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung CSE1L (CSE1L Antibody Abstract)
Hintergrund

Synonyms: CAS,Cellular apoptosis susceptibility protein,Chromosome segregation 1 (yeast homolog) like,Chromosome segregation 1 Like,Chromosome segregation 1 like protein,Chromosome segregation 1-like protein,Chromosome segregation gene CSE1,CSE 1,CSE 1 chromosome segregation 1 like,CSE 1 chromosome segregation 1 like protein,CSE 1L,CSE1,CSE1 chromosome segregation 1 like (yeast),CSE1 chromosome segregation 1 like,CSE1 chromosome segregation 1 like protein,CSE1L,Exp 2,Exp2,Exportin 2,Exportin-2,Exportin2,Importin alpha re exporter,Importin-alpha re-exporter,MGC117283,MGC130036,MGC130037,XPO 2,XPO2,XPO2

Background: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht

Observed_MW: 110kDa

Calculated_MW: 22kDa/103kDa/107kDa/110kDa

Gen-ID 1434
UniProt P55060
Pathways Protein targeting to Nucleus
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-CSE1 Chromosome Segregation 1-Like (Yeast) (CSE1L) antibody (ABIN6571992) Western blot analysis of extracts of various cell lines, using CSE1L antibody.
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