SART1 Antikörper

Produktnummer ABIN6571846

Dieser Anti-SART1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von SART1 in WB und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SART1 Antikörper (ABIN6571846)

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SART1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-SART1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human SART1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IP 1:20 - 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SART1

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Andere Bezeichnung: SART1

Hintergrund:

Synonyms: Ara 1,ARA1,HOMS 1,HOMS1,hSART 1,hSART1,hSnu 66,hSnu66,IgE autoantigen,MGC2038,SART 1,SART1 259,SART1(259) protein,SART1(800) protein,SART1259,Snu 66,Snu66 ,Squamous cell carcinoma antigen recognised by T cells,Squamous cell carcinoma antigen recognized by T cells 1,U4/U6.U5 tri snRNP associated 110 kDa protein ,U4/U6.U5 tri snRNP associated protein 1

Background: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

Molekulargewicht:

Observed_MW: 120kDa

Calculated_MW: 90kDa

Gen-ID: 9092

UniProt: O43290

Pathways: Ribonucleoprotein Complex Subunit Organization