GFRA4 Antikörper (AA 156-184)

Produktnummer ABIN657173

Der Kaninchen Polyklonal Anti-GFRA4-Antikörper wurde für WB validiert. Er ist geeignet, GFRA4 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für GFRA4 Antikörper (AA 156-184) (ABIN657173)

Target: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFRA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB33123

Produktdetails anti-GFRA4 Antikörper

Bindungsspezifität: AA 156-184

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GFRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human GFRA4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GFRA4 Antikörper (ABIN657173)

Wang, Guo, Wang, Liu, Zhang, Cui, Wu: "Downregulation of microRNA-483-5p Promotes Cell Proliferation and Invasion by Targeting GFRA4 in Hirschsprung's Disease." in: DNA and cell biology, Vol. 36, Issue 11, pp. 930-937, (2017) (PubMed).

Details zu GFRA4

Target: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Andere Bezeichnung: GFRA4

Hintergrund: The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 31670

NCBI Accession: NP_071422, NP_665705

UniProt: Q9GZZ7