PCDHa13 Antikörper

Produktnummer ABIN6571167

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PCDHa13 in WB. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für PCDHa13 Antikörper (ABIN6571167)

Target: PCDHa13 (Protocadherin alpha 13 (PCDHa13))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHa13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCDHa13 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PCDHA13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PCDHa13

Target: PCDHa13 (Protocadherin alpha 13 (PCDHa13))

Andere Bezeichnung: PCDHA13

Hintergrund:

Synonyms: Protocadherin Alpha 13,Ortholog Of Mouse CNR5,KIAA0345-Like 1,PCDH-Alpha-13,CNRS5,Protocadherin Alpha-13,PCDH-ALPHA13,CNRN5,CRNR5,CNR5

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molekulargewicht:

Observed_MW: 90kDa

Calculated_MW: 87kDa/102kDa

Gen-ID: 56136

UniProt: Q9Y5I0