ZAK Antikörper
Kurzübersicht für ZAK Antikörper (ABIN6571100)
Target
Alle ZAK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human ZAK (NP_598407.1).
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:50-1:200 IF 1:20-1:50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
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Andere Bezeichnung
- ZAK
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Hintergrund
- This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Molekulargewicht
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Observed_MW: 55kDa, 100kDa
Calculated_MW: 35kDa/51kDa/91kDa
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Gen-ID
- 51776
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UniProt
- Q9NYL2
Target
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