SEC63 Antikörper (N-Term)

Produktnummer ABIN657052

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SEC63 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SEC63 Antikörper (N-Term) (ABIN657052)

Target: SEC63 (SEC63 Homolog (SEC63))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC63 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB32397

Produktdetails anti-SEC63 Antikörper

Bindungsspezifität: AA 139-168, N-Term

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEC63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the N-terminal region of human SEC63.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu SEC63

Target: SEC63 (SEC63 Homolog (SEC63))

Andere Bezeichnung: SEC63

Hintergrund: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Molekulargewicht: 87997

NCBI Accession: NP_009145

UniProt: Q9UGP8

Pathways: ER-Nucleus Signaling