Dynamin 1-Like Antikörper

Produktnummer ABIN6569298

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Dynamin 1-Like in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Dynamin 1-Like Antikörper (ABIN6569298)

Target: Dynamin 1-Like (DNM1L)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Dynamin 1-Like Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human DNM1L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DRP1

Hintergrund:

Synonyms: DLP1,dnm1l,DNM1L,Dnm1p/Vps1p-like protein,dnml1,DRP1,DVLP,Dymple,Dynamin 1 like,Dynamin family member proline-rich carboxyl-terminal domain less,Dynamin like protein,Dynamin related protein 1,Dynamin-1-like protein,Dynamin-like protein 4,Dynamin-like protein,Dynamin-like protein IV,Dynamin-related protein 1,DYNIV 11,EMPF,EMPF1,FLJ41912,HdynIV,VPS1

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: 78-82kDa

Calculated_MW: 60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa

Gen-ID: 10059

UniProt: O00429