PHD1 Antikörper

Produktnummer ABIN6569199

Der Kaninchen Polyklonal Anti-PHD1-Antikörper wurde für WB und IP validiert. Er ist geeignet, PHD1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PHD1 Antikörper (ABIN6569199)

Target: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-PHD1 Antikörper

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human EGLN2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IP 1:20 - 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PHD1

Target: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Andere Bezeichnung: EGLN2

Hintergrund:

Synonyms: DKFZp434E026,EGL nine (C.elegans) homolog 2,Egl nine homolog 2 (C. elegans),Egl nine homolog 2,EGLN 2,EGLN2,EGLN2,EIT 6,EIT6,Estrogen-induced tag 6,HIF P4H 1,HIF PH1,HIF prolyl hydroxylase 1,HIF-PH1,HIF-prolyl hydroxylase 1,HIFPH 1,HIFPH1,HPH 3,HPH-1,HPH-3,HPH3,Hypoxia inducible factor prolyl hydroxylase 1,Hypoxia-inducible factor prolyl hydroxylase 1,P4H1,PHD 1,PhD1,prolyl hydroxylase domain containing protein 1,Prolyl hydroxylase domain-containing protein 1

Background: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.

Molekulargewicht:

Observed_MW: 55kDa

Calculated_MW: 40kDa/43kDa

Gen-ID: 112398

UniProt: Q96KS0

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis