Selectin E + CD62e Antikörper (Selectin E)

Details for Product anti-SELE Antibody No. ABIN6569172
Target
Reaktivität
Human, Maus
123
32
24
22
7
5
5
5
3
3
2
2
2
2
1
1
Wirt
Kaninchen
80
64
15
7
3
2
Klonalität
Polyklonal
Konjugat
Dieser Selectin E + CD62e Antikörper ist unkonjugiert
20
19
8
6
3
2
2
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
98
68
60
47
31
29
23
16
14
12
8
7
6
6
3
3
2
1
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human SELE
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung E-Selectin (SELE Antibody Abstract)
Hintergrund

Synonyms: CD26E,CD62 antigen-like family member E,CD62E,E selectin,E-selectin,ELAM,ELAM-1,ELAM1,Endothelial adhesion molecule 1,Endothelial leukocyte adhesion molecule 1,ESEL,LECAM2,Leukocyte-endothelial cell adhesion molecule 2,LYAM2,Sele,Selectin E

Background: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Molekulargewicht

Observed_MW: 68kDa

Calculated_MW: 66kDa

Gen-ID 6401
UniProt P16581
Pathways Thromboxane A2 Receptor Signaling
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Selectin E (SELE) antibody (ABIN6569172) Western blot analysis of extracts of various cell lines, using SELE antibody.
Image no. 2 for anti-Selectin E (SELE) antibody (ABIN6569172) Immunofluorescence analysis of MCF-7 cells using SELE antibody.
Image no. 3 for anti-Selectin E (SELE) antibody (ABIN6569172) Immunohistochemistry of paraffin-embedded human breast using SELE Antibody.
Image no. 4 for anti-Selectin E (SELE) antibody (ABIN6569172) Immunohistochemistry of paraffin-embedded human uterine cancer using SELE Antibody.